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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOLC1 All Species: 20
Human Site: S290 Identified Species: 33.85
UniProt: Q14978 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14978 NP_004732.2 699 73603 S290 K N K P G P Y S S V P P P S A
Chimpanzee Pan troglodytes XP_001171017 700 73581 S291 K N K P G P Y S S V P P P S A
Rhesus Macaque Macaca mulatta XP_001112196 701 73703 S291 K N K P G P Y S S V P P P S A
Dog Lupus familis XP_851848 704 74723 S297 K K K P G P Y S S V P P P S V
Cat Felis silvestris
Mouse Mus musculus O08784 1320 134983 A738 S V P A A G K A G A P A T Q A
Rat Rattus norvegicus P41777 704 73545 S300 K K K A G P Y S S V P P P S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511079 669 69188 E244 S S S E E E E E Q Q Q R K L A
Chicken Gallus gallus XP_421630 694 72200 S273 K P K S G Q Y S A V P P P Q A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689627 1001 102013 D495 K D D S S S S D S E S S E D E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_730693 686 70584 K248 P A V Q P A A K P A P K A A A
Honey Bee Apis mellifera XP_001120943 685 75016 I266 N A K P Q L P I K A K S N I K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796224 791 84162 G358 P V K A T P K G V K V N V S K
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001168628 517 55362 E123 R S G T E A G E P E S K A I E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32583 406 40997 P12 K I K V D E V P K L S V K E K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 94.2 81.5 N.A. 24.9 74.1 N.A. 50.7 43.6 N.A. 36.6 N.A. 27.3 22 N.A. 34.5
Protein Similarity: 100 98.8 95.5 85.6 N.A. 36.7 81.2 N.A. 60.3 57.5 N.A. 47.5 N.A. 42.3 42.9 N.A. 47.9
P-Site Identity: 100 100 100 86.6 N.A. 13.3 80 N.A. 6.6 66.6 N.A. 13.3 N.A. 13.3 13.3 N.A. 20
P-Site Similarity: 100 100 100 86.6 N.A. 20 80 N.A. 13.3 73.3 N.A. 20 N.A. 20 13.3 N.A. 20
Percent
Protein Identity: N.A. 23.6 N.A. N.A. 25.1 N.A.
Protein Similarity: N.A. 40.9 N.A. N.A. 39.4 N.A.
P-Site Identity: N.A. 0 N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. 13.3 N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 0 22 8 15 8 8 8 22 0 8 15 8 50 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 8 0 8 0 0 8 0 0 0 0 0 8 0 % D
% Glu: 0 0 0 8 15 15 8 15 0 15 0 0 8 8 15 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 43 8 8 8 8 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 0 8 0 0 0 0 0 15 0 % I
% Lys: 58 15 65 0 0 0 15 8 15 8 8 15 15 0 22 % K
% Leu: 0 0 0 0 0 8 0 0 0 8 0 0 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 22 0 0 0 0 0 0 0 0 0 8 8 0 0 % N
% Pro: 15 8 8 36 8 43 8 8 15 0 58 43 43 0 0 % P
% Gln: 0 0 0 8 8 8 0 0 8 8 8 0 0 15 0 % Q
% Arg: 8 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % R
% Ser: 15 15 8 15 8 8 8 43 43 0 22 15 0 43 0 % S
% Thr: 0 0 0 8 8 0 0 0 0 0 0 0 8 0 0 % T
% Val: 0 15 8 8 0 0 8 0 8 43 8 8 8 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 43 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _